Protein profile

PA4445

hypothetical protein

Genome: NC_002516.2

Gene: PA4445 Structure source: AlphaFold UniProt Q9HVX2

Export view

Amino acids 252

Annotations 2

Features 11

PDB binders 0

Druggability 0.465

Overview

Basic information about this protein and its source genome.

Accession: PA4445
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA4445
Status: annotated
Amino acids: 252
Structure source: AlphaFold

GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0046872 Binding to a metal ion.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.465

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0046872 Binding to a metal ion.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records

Show feature table

Start	End	DB	Term	Name
11	240	Pfam	PF01784	NIF3 (NGG1p interacting factor 3)
11	240	InterPro	IPR002678	DUF34/NIF3
99	223	Gene3D	G3DSA:3.40.1390.30	-
5	251	SUPERFAMILY	SSF102705	NIF3 (NGG1p interacting factor 3)-like
5	251	InterPro	IPR036069	DUF34/NIF3 superfamily
99	223	FunFam	G3DSA:3.40.1390.30:FF:000002	Nif3-like dinuclear metal center protein
8	240	Gene3D	G3DSA:3.40.1390.30	-
3	243	PANTHER	PTHR13799	NGG1 INTERACTING FACTOR 3
3	243	InterPro	IPR002678	DUF34/NIF3
6	251	NCBIfam	TIGR00486	Nif3-like dinuclear metal center hexameric protein
6	251	InterPro	IPR002678	DUF34/NIF3

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA4445	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
2				0.465