Protein profile

PA4452

hypothetical protein

Genome: NC_002516.2

Gene: PA4452 Structure source: AlphaFold UniProt Q9HVW5
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Amino acids 102
Annotations 0
Features 9
PDB binders 0
Druggability 0.761

Overview

Basic information about this protein and its source genome.

Accession
PA4452
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4452
Status
annotated
Amino acids
102
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.761
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MSQASLREGAAGELQLAGVLDYSSGPALREQGGRLIRASQAAELVVDCSAVERSSSVGISLLLAFIRDARKAGKVLSVRALPDDMREIAKVSSLLEILPLQE

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
7 100 SUPERFAMILY SSF52091 SpoIIaa-like
7 100 InterPro IPR036513 STAS domain superfamily
14 102 CDD cd07043 STAS_anti-anti-sigma_factors
14 94 Pfam PF13466 STAS domain
14 94 InterPro IPR002645 STAS domain
7 102 Gene3D G3DSA:3.30.750.24 STAS domain
7 102 InterPro IPR036513 STAS domain superfamily
14 102 ProSiteProfiles PS50801 STAS domain profile.
14 102 InterPro IPR002645 STAS domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4452
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.761