Protein profile

PA4473

hypothetical protein

Genome: NC_002516.2

Gene: PA4473 darP Structure source: AlphaFold UniProt Q9HVU8
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Amino acids 200
Annotations 4
Features 17
PDB binders 0
Druggability 0.673

Overview

Basic information about this protein and its source genome.

Accession
PA4473
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4473 darP
Status
annotated
Amino acids
200
Structure source
AlphaFold
GO
GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0043022 Binding to a ribosome. GO:0019843 Binding to a ribosomal RNA. GO:1902626 The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.673
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MAAHAAGPDKRPLTRYHGGVFHWTTTMAEFHDDDSQFEEKSKSQIKRELHALQDLGERLTTLQPQLLERLPLTDPLRKALLEAPKHKAHIARKRHIQYIGKLMRDQDVDAIVALIDQVDSSTRQYNERFHALERWRDQLIAGGDAALDAFVGEFPECDRQHLRGLVRHAQHEAAHNKPPAAARKVFKYIRELDETKRGLR

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

4 GO

Gene Ontology (GO)

4
  • GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
  • GO:0043022 Binding to a ribosome.
  • GO:0019843 Binding to a ribosomal RNA.
  • GO:1902626 The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.

Sequence Features

Domain/signature hits from InterPro and related databases.

17 records
Show feature table
Start End DB Term Name
39 190 Pfam PF04751 Protein of unknown function (DUF615)
39 190 InterPro IPR006839 Ribosome-associated, YjgA
29 194 Hamap MF_00765 UPF0307 protein YjgA [yjgA].
29 194 InterPro IPR006839 Ribosome-associated, YjgA
49 124 Gene3D G3DSA:1.10.60.30 -
49 124 InterPro IPR023153 PSPTO4464-like domain superfamily
24 198 PIRSF PIRSF016183 UCP016183
24 198 InterPro IPR006839 Ribosome-associated, YjgA
126 197 FunFam G3DSA:1.10.60.30:FF:000002 UPF0307 protein YjgA
28 197 PANTHER PTHR38101 UPF0307 PROTEIN YJGA
28 197 InterPro IPR006839 Ribosome-associated, YjgA
50 192 SUPERFAMILY SSF158710 PSPTO4464-like
50 192 InterPro IPR023153 PSPTO4464-like domain superfamily
39 191 CDD cd16331 YjgA-like
39 191 InterPro IPR006839 Ribosome-associated, YjgA
125 200 Gene3D G3DSA:1.10.60.30 -
125 200 InterPro IPR023153 PSPTO4464-like domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4473
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.673
1 0.637