Protein profile

PA4476

hypothetical protein

Genome: NC_002516.2

Gene: PA4476 Structure source: AlphaFold UniProt Q9HVU5
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Amino acids 1276
Annotations 1
Features 15
PDB binders 0
Druggability 0.932

Overview

Basic information about this protein and its source genome.

Accession
PA4476
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4476
Status
annotated
Amino acids
1276
Structure source
AlphaFold
GO
GO:0015914 The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
OuterMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.932
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0015914 The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
1 1275 PANTHER PTHR38690 PROTEASE-RELATED
1 1275 InterPro IPR011836 Conserved hypothetical protein CHP02099
1220 1239 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
33 1219 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1020 1265 Pfam PF13502 AsmA-like C-terminal region
1020 1265 InterPro IPR032712 AsmA-like, C-terminal
11 33 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
10 1275 NCBIfam TIGR02099 YhdP family protein
10 1275 InterPro IPR011836 Conserved hypothetical protein CHP02099
1220 1239 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 11 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
513 797 Pfam PF13116 Protein of unknown function
513 797 InterPro IPR025263 Domain of unknown function DUF3971
1240 1276 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
12 32 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4476
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.905
2 0.857