Protein profile

PA4486

hypothetical protein

Genome: NC_002516.2

Gene: PA4486 Structure source: AlphaFold UniProt Q9HVT5

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Amino acids 128

Annotations 1

Features 7

PDB binders 0

Druggability 0.585

Overview

Basic information about this protein and its source genome.

Accession: PA4486
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA4486
Status: annotated
Amino acids: 128
Structure source: AlphaFold

GO:0051920 Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.585

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0051920 Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records

Show feature table

Start	End	DB	Term	Name
35	117	Pfam	PF02627	Carboxymuconolactone decarboxylase family
35	117	InterPro	IPR003779	Carboxymuconolactone decarboxylase-like
5	119	SUPERFAMILY	SSF69118	AhpD-like
5	119	InterPro	IPR029032	AhpD-like
3	122	Gene3D	G3DSA:1.20.1290.10	-
3	122	InterPro	IPR029032	AhpD-like
3	124	PANTHER	PTHR33570	4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA4486	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.585