Protein profile

PA4516

hypothetical protein

Genome: NC_002516.2

Gene: PA4516 Structure source: AlphaFold UniProt Q9HVQ6
Export view
Amino acids 271
Annotations 1
Features 22
PDB binders 0
Druggability 0.818

Overview

Basic information about this protein and its source genome.

Accession
PA4516
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4516
Status
annotated
Amino acids
271
Structure source
AlphaFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
31.646
Human E-value
2.17e-06
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.818
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

22 records
Show feature table
Start End DB Term Name
114 147 Pfam PF08238 Sel1 repeat
114 147 InterPro IPR006597 Sel1-like repeat
148 183 Pfam PF08238 Sel1 repeat
148 183 InterPro IPR006597 Sel1-like repeat
236 250 Pfam PF08238 Sel1 repeat
236 250 InterPro IPR006597 Sel1-like repeat
77 110 Pfam PF08238 Sel1 repeat
77 110 InterPro IPR006597 Sel1-like repeat
202 215 Pfam PF08238 Sel1 repeat
202 215 InterPro IPR006597 Sel1-like repeat
41 75 Pfam PF08238 Sel1 repeat
41 75 InterPro IPR006597 Sel1-like repeat
13 268 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
13 268 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
70 182 PANTHER PTHR43628 ACTIVATOR OF C KINASE PROTEIN 1-RELATED
148 183 SMART SM00671 sel1
40 75 SMART SM00671 sel1
40 75 InterPro IPR006597 Sel1-like repeat
114 147 SMART SM00671 sel1
76 111 SMART SM00671 sel1
76 111 InterPro IPR006597 Sel1-like repeat
15 251 SUPERFAMILY SSF81901 HCP-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4516
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.818