Protein profile

PA4535

hypothetical protein

Genome: NC_002516.2

Gene: PA4535 Structure source: Experimental + AlphaFold UniProt Q9HVP2
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Amino acids 209
Annotations 0
Features 8
PDB binders 0
Druggability 0.957

Overview

Basic information about this protein and its source genome.

Accession
PA4535
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4535
Status
annotated
Amino acids
209
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.957
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
1 209 Gene3D G3DSA:3.40.1540.10 Protein of unknown function DUF1780, putative endonuclease
1 209 InterPro IPR037074 Protein of unknown function DUF1780, putative endonuclease superfamily
1 209 SUPERFAMILY SSF52980 Restriction endonuclease-like
1 209 InterPro IPR011335 Restriction endonuclease type II-like
6 203 CDD cd22342 Pa4535-like
6 203 InterPro IPR014796 Protein of unknown function DUF1780, putative endonuclease
2 209 Pfam PF08682 Putative endonuclease, protein of unknown function (DUF1780)
2 209 InterPro IPR014796 Protein of unknown function DUF1780, putative endonuclease

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 1Y0K
X-ray 1.75 Å A
100.0% 1-209
PDBe RCSB PDBj File
Viewing
AlphaFold PA4535
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.957
4 0.592
3 0.357
2 0.239

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.24 0.055