Target Pathogen

Overview

Basic information about this protein and its source genome.

Accession: PA4563
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: rpsT PA4563
Status: annotated
Amino acids: 91
Structure source: AlphaFold

GO

GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0015935 The smaller of the two subunits of a ribosome. GO:0070181 Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA. GO:0003735 The action of a molecule that contributes to the structural integrity of the ribosome. GO:0006412 The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. GO:0003723 Binding to an RNA molecule or a portion thereof.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Cytoplasmic

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

7 GO

Gene Ontology (GO)

7

GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0015935 The smaller of the two subunits of a ribosome.
GO:0070181 Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.
GO:0003735 The action of a molecule that contributes to the structural integrity of the ribosome.
GO:0006412 The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
GO:0003723 Binding to an RNA molecule or a portion thereof.
GO:0005840 An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records

Show feature table

Start	End	DB	Term	Name
3	88	PANTHER	PTHR33398	30S RIBOSOMAL PROTEIN S20
3	88	InterPro	IPR002583	Ribosomal protein S20
1	23	MobiDBLite	mobidb-lite	consensus disorder prediction
1	87	FunFam	G3DSA:1.20.58.110:FF:000001	30S ribosomal protein S20
1	84	NCBIfam	TIGR00029	30S ribosomal protein S20
1	84	InterPro	IPR002583	Ribosomal protein S20
1	85	Hamap	MF_00500	30S ribosomal protein S20 [rpsT].
1	85	InterPro	IPR002583	Ribosomal protein S20
3	86	SUPERFAMILY	SSF46992	Ribosomal protein S20
3	86	InterPro	IPR036510	Ribosomal protein S20 superfamily
1	87	Gene3D	G3DSA:1.20.58.110	Ribosomal protein S20
1	87	InterPro	IPR036510	Ribosomal protein S20 superfamily
2	83	Pfam	PF01649	Ribosomal protein S20
2	83	InterPro	IPR002583	Ribosomal protein S20

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

No pockets are loaded yet for the displayed AlphaFold model PA4563 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA4563	AlphaFold	—	—	full sequence	—	Viewing