Protein profile

PA4636

hypothetical protein

Genome: NC_002516.2

Gene: PA4636 Structure source: AlphaFold UniProt Q9HVF5
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Amino acids 386
Annotations 3
Features 5
PDB binders 0
Druggability 0.882

Overview

Basic information about this protein and its source genome.

Accession
PA4636
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4636
Status
annotated
Amino acids
386
Structure source
AlphaFold
GO
GO:0016746 Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). GO:0019698 The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. GO:0042840 The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.882
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0016746 Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
  • GO:0019698 The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.
  • GO:0042840 The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate.

Sequence Features

Domain/signature hits from InterPro and related databases.

5 records
Show feature table
Start End DB Term Name
382 386 Coils Coil Coil
90 210 Pfam PF01553 Acyltransferase
90 210 InterPro IPR002123 Phospholipid/glycerol acyltransferase
89 239 SUPERFAMILY SSF69593 Glycerol-3-phosphate (1)-acyltransferase
6 382 PANTHER PTHR30068 URONATE ISOMERASE

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4636
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.64
1 0.516