Protein profile

PA4649

hypothetical protein

Genome: NC_002516.2

Gene: PA4649 Structure source: AlphaFold UniProt Q9HVE3
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Amino acids 177
Annotations 0
Features 12
PDB binders 0
Druggability 0.91

Overview

Basic information about this protein and its source genome.

Accession
PA4649
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4649
Status
annotated
Amino acids
177
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Extracellular

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.91
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
1 12 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 28 SignalP_EUK SignalP-noTM SignalP-noTM
24 28 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 28 Phobius SIGNAL_PEPTIDE Signal peptide region
119 174 SMART SM00972 SCPU_a_2_a
119 174 InterPro IPR007893 Spore coat protein U
13 23 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
30 174 Pfam PF05229 Spore Coat Protein U domain
30 174 InterPro IPR007893 Spore coat protein U
4 177 PANTHER PTHR37089 PROTEIN U-RELATED
1 28 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
29 177 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4649
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.91