Protein profile

PA4650

hypothetical protein

Genome: NC_002516.2

Gene: PA4650 Structure source: AlphaFold UniProt Q9HVE2
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Amino acids 180
Annotations 2
Features 14
PDB binders 0
Druggability 0.935

Overview

Basic information about this protein and its source genome.

Accession
PA4650
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4650
Status
annotated
Amino acids
180
Structure source
AlphaFold
GO
GO:0009289 A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0007155 The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.935
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0009289 A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.
  • GO:0007155 The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
25 180 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 24 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
8 17 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
2 180 PANTHER PTHR37089 PROTEIN U-RELATED
119 177 SMART SM00972 SCPU_a_2_a
119 177 InterPro IPR007893 Spore coat protein U
1 24 SignalP_EUK SignalP-noTM SignalP-noTM
1 24 Phobius SIGNAL_PEPTIDE Signal peptide region
31 177 Pfam PF05229 Spore Coat Protein U domain
31 177 InterPro IPR007893 Spore coat protein U
32 180 Gene3D G3DSA:2.60.40.1090 -
32 180 InterPro IPR036937 Fimbrial-type adhesion domain superfamily
18 24 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4650
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.935