Protein profile

PA4653

hypothetical protein

Genome: NC_002516.2

Gene: PA4653 Structure source: AlphaFold UniProt Q9HVD9
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Amino acids 315
Annotations 0
Features 17
PDB binders 0
Druggability 0.736

Overview

Basic information about this protein and its source genome.

Accession
PA4653
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4653
Status
annotated
Amino acids
315
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.736
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MSRHSTSACLLGFATLCASPLLLAACTTSSGTGNFGSLSSFTVASTAQTITGTTGFKCTGSLLSILSTNTIDATIASTANPLGTTPRLYNAASGTYLPYSICKDNGCGTVYNVGSTVRWSSTTFLGILGLFNATDGSLPLYLRTATGVTLPAGTYTDTIGLNWAWHLCAAGIGPVCVYDDGTASSSVNVTLTVLKDCFIDSAPDLSFGSAALVSAFTAVNQNIGVRCTLNATYTIGFDNGNNFSGGWRRMLSGANAIQYNLYKPGDSTVWTTSNTQAGTGSGAAQNVPYRAIVNPAQGNVPAGTYSDTVRVILTY

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

17 records
Show feature table
Start End DB Term Name
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 26 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
25 315 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 24 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
20 24 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
137 315 PANTHER PTHR37089 PROTEIN U-RELATED
14 160 Pfam PF05229 Spore Coat Protein U domain
14 160 InterPro IPR007893 Spore coat protein U
185 311 Pfam PF05229 Spore Coat Protein U domain
185 311 InterPro IPR007893 Spore coat protein U
1 24 Phobius SIGNAL_PEPTIDE Signal peptide region
8 19 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 24 SignalP_EUK SignalP-noTM SignalP-noTM
257 312 SMART SM00972 SCPU_a_2_a
257 312 InterPro IPR007893 Spore coat protein U
97 162 SMART SM00972 SCPU_a_2_a
97 162 InterPro IPR007893 Spore coat protein U

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4653
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.736
1 0.715