Protein profile

PA4681

hypothetical protein

Genome: NC_002516.2

Gene: PA4681 Structure source: AlphaFold UniProt Q9HVB4
Export view
Amino acids 339
Annotations 0
Features 7
PDB binders 0
Druggability 0.668

Overview

Basic information about this protein and its source genome.

Accession
PA4681
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4681
Status
annotated
Amino acids
339
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.668
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MSRACLLAALLAAPFAHAEMTALDDEQLSDVQGAGIGFVLDSAMVDGNKATIAINGVTNTATGQNVPITVKELYVAATGSNKGSTLAPVTLGRLNFPFKLNLAKGSVLTTQLDDGRVVSTLPDTADVIELAFPSLVSGAGGQPCIAGYAGAGSNCSSRASEKVDAGIRFDFGVTSTRTDVLNLDFSELAMDGSYLRFWGANARSQLVGEIRLNLYAKTFEIMSCGAGSPSCVSAAEQAARTVYLTNAYASVALGYGKSQPLLFSVTADGNFTFELPKLTLANAADFYANAPRTSLVIENLNIGGTRPGYGQVPTGGYNMGRNEISGLSFNYLKVTSHNL

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
4 13 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
19 339 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 18 Phobius SIGNAL_PEPTIDE Signal peptide region
14 18 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 18 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 18 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4681
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.323
6 0.276
4 0.263