Protein profile

PA4735

hypothetical protein

Genome: NC_002516.2

Gene: PA4735 Structure source: AlphaFold UniProt Q9HV64
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Amino acids 1088
Annotations 2
Features 20
PDB binders 0
Druggability 0.925

Overview

Basic information about this protein and its source genome.

Accession
PA4735
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4735
Status
annotated
Amino acids
1088
Structure source
AlphaFold
GO
GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0090313 Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
OuterMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.925
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
  • GO:0090313 Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

20 records
Show feature table
Start End DB Term Name
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
36 1088 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
7 1087 PANTHER PTHR30441 UNCHARACTERIZED
445 466 MobiDBLite mobidb-lite consensus disorder prediction
327 475 MobiDBLite mobidb-lite consensus disorder prediction
898 1078 Gene3D G3DSA:3.30.1330.60 -
898 1078 InterPro IPR036737 OmpA-like domain superfamily
8 27 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
9 31 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
383 423 MobiDBLite mobidb-lite consensus disorder prediction
1 35 Phobius SIGNAL_PEPTIDE Signal peptide region
692 837 Pfam PF05359 Domain of Unknown Function (DUF748)
692 837 InterPro IPR008023 Protein of unknown function DUF748
476 626 Pfam PF05359 Domain of Unknown Function (DUF748)
476 626 InterPro IPR008023 Protein of unknown function DUF748
140 291 Pfam PF05359 Domain of Unknown Function (DUF748)
140 291 InterPro IPR008023 Protein of unknown function DUF748
28 35 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
904 945 SUPERFAMILY SSF103088 OmpA-like
904 945 InterPro IPR036737 OmpA-like domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4735
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.925
3 0.812