Protein profile

PA4739

hypothetical protein

Genome: NC_002516.2

Gene: PA4739 Structure source: AlphaFold UniProt Q9HV60

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Amino acids 114

Annotations 1

Features 16

PDB binders 0

Druggability 0.572

Overview

Basic information about this protein and its source genome.

Accession: PA4739
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA4739
Status: annotated
Amino acids: 114
Structure source: AlphaFold

GO:0042597 The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Periplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.572

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0042597 The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records

Show feature table

Start	End	DB	Term	Name
1	5	Phobius	SIGNAL_PEPTIDE_N_REGION	N-terminal region of a signal peptide.
45	108	Pfam	PF04972	BON domain
45	108	InterPro	IPR007055	BON domain
1	25	SignalP_GRAM_POSITIVE	SignalP-TM	SignalP-TM
18	25	Phobius	SIGNAL_PEPTIDE_C_REGION	C-terminal region of a signal peptide.
45	114	ProSiteProfiles	PS50914	BON domain profile.
45	114	InterPro	IPR007055	BON domain
33	108	PANTHER	PTHR34606	BON DOMAIN-CONTAINING PROTEIN
1	25	SignalP_GRAM_NEGATIVE	SignalP-noTM	SignalP-noTM
6	17	Phobius	SIGNAL_PEPTIDE_H_REGION	Hydrophobic region of a signal peptide.
50	113	SMART	SM00749	bon
50	113	InterPro	IPR014004	Transport-associated and nodulation domain, bacteria
26	114	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
47	111	FunFam	G3DSA:3.30.1340.30:FF:000001	Molecular chaperone OsmY
47	108	Gene3D	G3DSA:3.30.1340.30	-
1	25	Phobius	SIGNAL_PEPTIDE	Signal peptide region

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA4739	AlphaFold	—	—	full sequence	—	Viewing

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Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.572