Protein profile

PA4800

hypothetical protein

Genome: NC_002516.2

Gene: PA4800 Structure source: AlphaFold UniProt Q9HV09
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Amino acids 266
Annotations 2
Features 8
PDB binders 0
Druggability 0.641

Overview

Basic information about this protein and its source genome.

Accession
PA4800
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4800
Status
annotated
Amino acids
266
Structure source
AlphaFold
GO
GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0008757 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.641
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MTDLEHAVESNRRAWDASADSHLRGGGWQELSLAVQETGFSCLDETLAGVLRNLDLAGKAAVQVGCNNGREVLSLYAFGVARAVGIDQSAAFLAQARQLAERSPHQPRFVEANAYELPAELNGQFDLLLITIGVLNWMPDIARFFASVSGLLKPGGQLAIYETHPFLEMLEPESERPFELRNDYFTDTPHVSREAIVYEGSGSDTGIASYWYVHPLGDILGGLLGAGLRLSHFKEYPHSNREELYDLYEDGPLAIPMCYTLVAVKA

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule.
  • GO:0008757 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
63 160 Pfam PF08241 Methyltransferase domain
63 160 InterPro IPR013216 Methyltransferase type 11
64 169 PANTHER PTHR43464 METHYLTRANSFERASE
64 160 CDD cd02440 AdoMet_MTases
55 249 SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases
55 249 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
50 256 Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39
50 256 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA4800
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.641
2 0.632