Protein profile

PA4803

hypothetical protein

Genome: NC_002516.2

Gene: PA4803 Structure source: AlphaFold UniProt Q9HV06

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Amino acids 205

Annotations 1

Features 8

PDB binders 0

Druggability 0.773

Overview

Basic information about this protein and its source genome.

Accession: PA4803
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA4803
Status: annotated
Amino acids: 205
Structure source: AlphaFold

GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule.

Target profile

Computed evidence for target prioritization.

Human off-target: hit
Human identity (%): 22.302
Human E-value: 3.34e-08
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.773

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
1	203	Gene3D	G3DSA:3.40.50.150	Vaccinia Virus protein VP39
1	203	InterPro	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily
3	204	PANTHER	PTHR12843	PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10
46	144	Pfam	PF08241	Methyltransferase domain
46	144	InterPro	IPR013216	Methyltransferase type 11
3	189	SUPERFAMILY	SSF53335	S-adenosyl-L-methionine-dependent methyltransferases
3	189	InterPro	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily
44	149	CDD	cd02440	AdoMet_MTases

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA4803	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.773