Overview
Basic information about this protein and its source genome.
- Accession
- PA4851
- Gene
- PA4851
- Status
- annotated
- Amino acids
- 421
- Structure source
- AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Cytoplasmic
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 6 | 41 | NCBIfam | TIGR02098 | MJ0042 family finger-like domain |
| 6 | 41 | InterPro | IPR011723 | Zinc finger/thioredoxin putative |
| 267 | 287 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. |
| 53 | 78 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 200 | 215 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 267 | 289 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. |
| 126 | 147 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 6 | 41 | Pfam | PF13719 | zinc-ribbon domain |
| 288 | 421 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. |
| 272 | 416 | Pfam | PF11906 | Protein of unknown function (DUF3426) |
| 272 | 416 | InterPro | IPR021834 | Protein of unknown function DUF3426 |
| 176 | 190 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 126 | 246 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 61 | 75 | MobiDBLite | mobidb-lite | consensus disorder prediction |
| 1 | 266 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
PA4851
|
AlphaFold | — | — | full sequence | — | Viewing |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 2 | 0.354 | ||||||
| 8 | 0.328 | ||||||
| 4 | 0.254 |