Protein profile

PA4972

hypothetical protein

Genome: NC_002516.2

Gene: PA4972 Structure source: Experimental + AlphaFold UniProt Q9HUJ3
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Amino acids 248
Annotations 0
Features 12
PDB binders 0
Druggability 0.652

Overview

Basic information about this protein and its source genome.

Accession
PA4972
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA4972
Status
annotated
Amino acids
248
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.652
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
6 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
154 248 Gene3D G3DSA:3.90.640.20 -
154 248 InterPro IPR037126 PdaC/RsiV-like superfamily
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
1 19 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
1 5 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 18 SignalP_EUK SignalP-noTM SignalP-noTM
22 248 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
17 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 23 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
23 153 Gene3D G3DSA:3.30.565.40 -
1 23 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 4E72
X-ray 2.15 Å A
90.7% 24-248
PDBe RCSB PDBj File
Viewing
AlphaFold PA4972
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.401
1 0.387
5 0.271
4 0.21