Protein profile

PA5026

hypothetical protein

Genome: NC_002516.2

Gene: PA5026 Structure source: Experimental + AlphaFold UniProt Q9HUE3
Export view
Amino acids 150
Annotations 0
Features 6
PDB binders 0
Druggability 0.874

Overview

Basic information about this protein and its source genome.

Accession
PA5026
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5026
Status
annotated
Amino acids
150
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.874
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
13 137 Pfam PF14539 Domain of unknown function (DUF4442)
13 137 InterPro IPR027961 Protein of unknown function DUF4442
11 145 SUPERFAMILY SSF54637 Thioesterase/thiol ester dehydrase-isomerase
11 145 InterPro IPR029069 HotDog domain superfamily
1 150 Gene3D G3DSA:3.10.129.10 Hotdog Thioesterase
23 142 CDD cd03443 PaaI_thioesterase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 1SH8
X-ray 1.50 Å A,B
100.0% 1-150
PDBe RCSB PDBj File
Viewing
AlphaFold PA5026
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.874

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 7.82 0.415
2 2.03 0.045
3 1.41 0.018