Protein profile

PA5064

hypothetical protein

Genome: NC_002516.2

Gene: PA5064 ubiJ Structure source: AlphaFold UniProt Q9HUB9
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Amino acids 208
Annotations 3
Features 14
PDB binders 0
Druggability 0.981

Overview

Basic information about this protein and its source genome.

Accession
PA5064
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5064 ubiJ
Status
annotated
Amino acids
208
Structure source
AlphaFold
GO
GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0006744 The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. GO:0032150 OBSOLETE. The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.981
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
  • GO:0006744 The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
  • GO:0032150 OBSOLETE. The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
183 203 Coils Coil Coil
29 122 SUPERFAMILY SSF55718 SCP-like
29 122 InterPro IPR036527 SCP2 sterol-binding domain superfamily
17 114 Pfam PF02036 SCP-2 sterol transfer family
17 114 InterPro IPR003033 SCP2 sterol-binding domain
14 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 205 PANTHER PTHR38693 UBIQUINONE BIOSYNTHESIS PROTEIN UBIJ
1 205 InterPro IPR038989 Ubiquinone biosynthesis accessory factor UbiJ
3 13 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
7 203 Hamap MF_02215 Ubiquinone biosynthesis accessory factor UbiJ [ubiJ].
7 203 InterPro IPR038989 Ubiquinone biosynthesis accessory factor UbiJ
1 2 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
23 208 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA5064
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.981