Protein profile

PA5081

hypothetical protein

Genome: NC_002516.2

Gene: PA5081 Structure source: AlphaFold UniProt Q9HUA2

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Amino acids 158

Annotations 1

Features 9

PDB binders 0

Druggability 0.428

Overview

Basic information about this protein and its source genome.

Accession: PA5081
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA5081
Status: annotated
Amino acids: 158
Structure source: AlphaFold

GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.428

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records

Show feature table

Start	End	DB	Term	Name
3	154	PANTHER	PTHR43046	GDP-MANNOSE MANNOSYL HYDROLASE
9	127	Pfam	PF00293	NUDIX domain
9	127	InterPro	IPR000086	NUDIX hydrolase domain
5	142	ProSiteProfiles	PS51462	Nudix hydrolase domain profile.
5	142	InterPro	IPR000086	NUDIX hydrolase domain
10	138	CDD	cd02883	Nudix_Hydrolase
2	144	Gene3D	G3DSA:3.90.79.10	Nucleoside Triphosphate Pyrophosphohydrolase
5	133	SUPERFAMILY	SSF55811	Nudix
5	133	InterPro	IPR015797	NUDIX hydrolase-like domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA5081	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.428