Protein profile

PA5087

hypothetical protein

Genome: NC_002516.2

Gene: PA5087 Structure source: Experimental + AlphaFold UniProt Q9HU96
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Amino acids 289
Annotations 1
Features 21
PDB binders 0
Druggability 0.671

Overview

Basic information about this protein and its source genome.

Accession
PA5087
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5087
Status
annotated
Amino acids
289
Structure source
Experimental + AlphaFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
28.916
Human E-value
8.42e-10
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.671
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MAIGLWAVLCLAGVPVMANSKPFVCANEKDHLPPLDPQADAWYREAAALAKPDTLRPWGRIVEIYSKAVERGHWKAMHNLANLYRTGWPGGVEKDPQKALDLYQKMIDLDVPQGFYDMGAMIGNRAGVKNPATDGLTFLDKAASLGNPPALTELGKLYIYVAKEKELGLAYASCASSQGYAPASYELGSYYELVENNYPKALSYYQVSVSQGGRSAAFFLSRVFGKRTPPSSAMWYTPDEKLEKFYYSLYLQIDADPDLRFPNLVKYNPLPPHPVQGYDAARPDWKPGQ

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

21 records
Show feature table
Start End DB Term Name
181 213 SMART SM00671 sel1
181 213 InterPro IPR006597 Sel1-like repeat
112 147 SMART SM00671 sel1
112 147 InterPro IPR006597 Sel1-like repeat
148 180 SMART SM00671 sel1
148 180 InterPro IPR006597 Sel1-like repeat
74 111 SMART SM00671 sel1
74 111 InterPro IPR006597 Sel1-like repeat
1 20 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
49 219 PANTHER PTHR11102 SEL-1-LIKE PROTEIN
1 18 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
2 13 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
38 158 SUPERFAMILY SSF81901 HCP-like
1 1 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 18 Phobius SIGNAL_PEPTIDE Signal peptide region
130 225 SUPERFAMILY SSF81901 HCP-like
14 18 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
37 254 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
37 254 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
19 289 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 18 SignalP_EUK SignalP-noTM SignalP-noTM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 5JKP
X-ray 2.11 Å A
93.4% 20-289
PDBe RCSB PDBj File
Viewing
AlphaFold PA5087
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.671
6 0.464
2 0.241
8 0.232

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.2 0.11
2 1.58 0.025
3 1.49 0.021
4 1.44 0.019
5 1.35 0.015