Protein profile

PA5088

hypothetical protein

Genome: NC_002516.2

Gene: PA5088 Structure source: Experimental + AlphaFold UniProt Q9HU95
Export view
Amino acids 293
Annotations 1
Features 23
PDB binders 0
Druggability 0.588

Overview

Basic information about this protein and its source genome.

Accession
PA5088
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5088
Status
annotated
Amino acids
293
Structure source
Experimental + AlphaFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
29.319
Human E-value
2.43e-07
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.588
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

23 records
Show feature table
Start End DB Term Name
22 293 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
5 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 21 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
17 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
268 293 MobiDBLite mobidb-lite consensus disorder prediction
42 162 SUPERFAMILY SSF81901 HCP-like
131 225 SUPERFAMILY SSF81901 HCP-like
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
60 241 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
60 241 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
185 217 SMART SM00671 sel1
185 217 InterPro IPR006597 Sel1-like repeat
152 184 SMART SM00671 sel1
152 184 InterPro IPR006597 Sel1-like repeat
78 115 SMART SM00671 sel1
78 115 InterPro IPR006597 Sel1-like repeat
1 4 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
50 228 PANTHER PTHR11102 SEL-1-LIKE PROTEIN
1 21 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
186 217 Pfam PF08238 Sel1 repeat
186 217 InterPro IPR006597 Sel1-like repeat
79 112 Pfam PF08238 Sel1 repeat
79 112 InterPro IPR006597 Sel1-like repeat

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 5JJO
X-ray 2.00 Å A
92.8% 22-293
PDBe RCSB PDBj File
Viewing
AlphaFold PA5088
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.588
7 0.359
5 0.316

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.35 0.015
2 1.34 0.015