Overview
Basic information about this protein and its source genome.
- Accession
- PA5104
- Gene
- PA5104
- Status
- annotated
- Amino acids
- 196
- Structure source
- Experimental + AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Unknown
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 11 | 187 | Pfam | PF05962 | HutD |
| 11 | 187 | InterPro | IPR010282 | Uncharacterised protein family HutD/Ves |
| 22 | 113 | CDD | cd20293 | cupin_HutD_N |
| 9 | 117 | Gene3D | G3DSA:2.60.120.10 | Jelly Rolls |
| 9 | 117 | InterPro | IPR014710 | RmlC-like jelly roll fold |
| 4 | 190 | SUPERFAMILY | SSF51182 | RmlC-like cupins |
| 4 | 190 | InterPro | IPR011051 | RmlC-like cupin domain superfamily |
| 3 | 194 | PANTHER | PTHR37943 | PROTEIN VES |
| 3 | 194 | InterPro | IPR010282 | Uncharacterised protein family HutD/Ves |
| 118 | 193 | CDD | cd20490 | cupin_HutD_C |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
1 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 1 | 0.538 | ||||||
| 2 | 0.242 |
Pockets (P2RANK)
Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).
| P2RANK | Sticks | Spheres | Surfaces | Score | Probability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|---|
| 1 | 10.58 | 0.569 | ||||||
| 2 | 1.45 | 0.019 | ||||||
| 3 | 1.0 | 0.005 |
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 3 | 0.468 | ||||||
| 1 | 0.293 |