Protein profile

PA5109

hypothetical protein

Genome: NC_002516.2

Gene: PA5109 Structure source: AlphaFold UniProt Q9HU74
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Amino acids 200
Annotations 1
Features 7
PDB binders 0
Druggability 0.698

Overview

Basic information about this protein and its source genome.

Accession
PA5109
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5109
Status
annotated
Amino acids
200
Structure source
AlphaFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.698
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MSAPWETLLDWWFGTSSDAAEVVAQRNGLWFGKNVCQDADAGGRFGDLVNQALDGGLQEWTAEADGWLALILLLDQLPRMIYRDTPRAYAGDARAQRVVREGLEKGFDRQLPPVRRVFAYLVLEHAEDLPSQERAVACFRDLRDQVGGSVRKPFDDFYDYAERHHAVVARFGRFPHRNAILGRPSSEEETAFLREPGSRF

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
2 89 Gene3D G3DSA:1.20.58.320 -
90 200 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
90 200 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
9 197 Pfam PF06041 Bacterial protein of unknown function (DUF924)
9 197 InterPro IPR010323 Protein of unknown function DUF924
3 196 SUPERFAMILY SSF48452 TPR-like
3 196 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA5109
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.698