Protein profile

PA5130

hypothetical protein

Genome: NC_002516.2

Gene: PA5130 Structure source: AlphaFold UniProt Q9HU54
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Amino acids 139
Annotations 1
Features 16
PDB binders 0
Druggability 0.901

Overview

Basic information about this protein and its source genome.

Accession
PA5130
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5130
Status
annotated
Amino acids
139
Structure source
AlphaFold
GO
GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.901
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
12 30 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
7 29 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
43 131 Pfam PF00581 Rhodanese-like domain
43 131 InterPro IPR001763 Rhodanese-like domain
16 139 SUPERFAMILY SSF52821 Rhodanese/Cell cycle control phosphatase
16 139 InterPro IPR036873 Rhodanese-like domain superfamily
40 136 SMART SM00450 rhod_4
40 136 InterPro IPR001763 Rhodanese-like domain
41 139 Gene3D G3DSA:3.40.250.10 -
41 139 InterPro IPR036873 Rhodanese-like domain superfamily
31 139 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
50 139 ProSiteProfiles PS50206 Rhodanese domain profile.
50 139 InterPro IPR001763 Rhodanese-like domain
44 131 CDD cd00158 RHOD
1 11 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
34 137 PANTHER PTHR43031 FAD-DEPENDENT OXIDOREDUCTASE

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA5130
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.901
2 0.304