Protein profile

PA5148

hypothetical protein

Genome: NC_002516.2

Gene: PA5148 Structure source: Experimental + AlphaFold UniProt Q9HU36
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Amino acids 90
Annotations 3
Features 12
PDB binders 0
Druggability 0.674

Overview

Basic information about this protein and its source genome.

Accession
PA5148
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5148
Status
annotated
Amino acids
90
Structure source
Experimental + AlphaFold
GO
GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0005506 Binding to an iron (Fe) ion. GO:0034599 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.674
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MSRTVMCRKYHEELPGLDRPPYPGAKGEDIYNNVSRKAWDEWQKHQTMLINERRLNMMNAEDRKFLQQEMDKFLSGEDYAKADGYVPPSA

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
  • GO:0005506 Binding to an iron (Fe) ion.
  • GO:0034599 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
1 89 SUPERFAMILY SSF111148 YggX-like
1 89 InterPro IPR036766 Fe(II) trafficking protein YggX superfamily
1 88 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX].
1 88 InterPro IPR007457 Fe(II) trafficking protein YggX
1 89 PANTHER PTHR36965 FE(2+)-TRAFFICKING PROTEIN-RELATED
1 89 InterPro IPR007457 Fe(II) trafficking protein YggX
1 90 FunFam G3DSA:1.10.3880.10:FF:000001 Probable Fe(2+)-trafficking protein
1 88 Pfam PF04362 Bacterial Fe(2+) trafficking
1 90 PIRSF PIRSF029827 Fe_traffic_YggX
1 90 InterPro IPR007457 Fe(II) trafficking protein YggX
1 90 Gene3D G3DSA:1.10.3880.10 Fe(II) trafficking protein YggX
1 90 InterPro IPR036766 Fe(II) trafficking protein YggX superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 1T07
X-ray 1.80 Å A
100.0% 1-90
PDBe RCSB PDBj File
Viewing
AlphaFold PA5148
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 0.67 0.001