Protein profile

PA5178

hypothetical protein

Genome: NC_002516.2

Gene: PA5178 Structure source: AlphaFold UniProt Q9HU11
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Amino acids 145
Annotations 3
Features 18
PDB binders 0
Druggability 0.777

Overview

Basic information about this protein and its source genome.

Accession
PA5178
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5178
Status
annotated
Amino acids
145
Structure source
AlphaFold
GO
GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0030955 Binding to a potassium ion (K+). GO:0035864 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.777
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
  • GO:0030955 Binding to a potassium ion (K+).
  • GO:0035864 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.

Sequence Features

Domain/signature hits from InterPro and related databases.

18 records
Show feature table
Start End DB Term Name
96 144 Pfam PF01476 LysM domain
96 144 InterPro IPR018392 LysM domain
94 143 CDD cd00118 LysM
94 143 InterPro IPR018392 LysM domain
92 145 Gene3D G3DSA:3.10.350.10 LysM domain
92 145 InterPro IPR036779 LysM domain superfamily
94 144 SUPERFAMILY SSF54106 LysM domain
94 144 InterPro IPR036779 LysM domain superfamily
95 144 SMART SM00257 LysM_2
95 144 InterPro IPR018392 LysM domain
21 87 Gene3D G3DSA:3.30.1340.30 -
94 143 ProSiteProfiles PS51782 LysM domain profile.
22 87 Pfam PF04972 BON domain
22 87 InterPro IPR007055 BON domain
20 88 ProSiteProfiles PS50914 BON domain profile.
20 88 InterPro IPR007055 BON domain
93 145 FunFam G3DSA:3.10.350.10:FF:000001 Peptidoglycan-binding protein LysM
21 87 FunFam G3DSA:3.30.1340.30:FF:000002 LysM domain/BON superfamily protein

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA5178
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.777
4 0.362