Protein profile

PA5182

hypothetical protein

Genome: NC_002516.2

Gene: NP_253869.2 Structure source: ColabFold
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Amino acids 171
Annotations 0
Features 7
PDB binders 0
Druggability 0.692

Overview

Basic information about this protein and its source genome.

Accession
PA5182
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
NP_253869.2
Status
annotated
Amino acids
171
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.692
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MKYSSILLLSLSLVGSTAFAGDDTRAAIGGALGGVLGSVVGDAVGGSTGAAIGSGIGGAAGGAVGAGRGNKTEAAIGGGLGAAGGNVIGRQIGGSTGGLIGAALGGAGGGALGNHYGDGNRRYDDDDDYRDRRYYRRAGYRDGYYRHDNGHHYGQYKKWKRHKHHRRYYDD

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
21 171 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 20 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 20 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
16 20 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 20 Phobius SIGNAL_PEPTIDE Signal peptide region
4 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold PA5182
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.692