Protein profile

PA5208

hypothetical protein

Genome: NC_002516.2

Gene: PA5208 Structure source: AlphaFold UniProt Q9HTY2

Export view

Amino acids 225

Annotations 2

Features 11

PDB binders 0

Druggability 0.907

Overview

Basic information about this protein and its source genome.

Accession: PA5208
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA5208
Status: annotated
Amino acids: 225
Structure source: AlphaFold

GO:0071978 Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria. GO:0044010 A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.907

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

GO:0071978 Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria.
GO:0044010 A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records

Show feature table

Start	End	DB	Term	Name
37	209	SUPERFAMILY	SSF109755	PhoU-like
1	225	Gene3D	G3DSA:1.20.58.220	Phosphate transport system protein phou homolog 2; domain 2
1	225	InterPro	IPR038078	PhoU-like domain superfamily
1	225	PANTHER	PTHR36536	UPF0111 PROTEIN HI_1603
1	225	InterPro	IPR002727	Protein of unknown function DUF47
47	67	Coils	Coil	Coil
7	224	Pfam	PF01865	Protein of unknown function DUF47
7	224	InterPro	IPR018445	Putative phosphate transport regulator
158	178	Coils	Coil	Coil
8	224	NCBIfam	TIGR00153	TIGR00153 family protein
8	224	InterPro	IPR002727	Protein of unknown function DUF47

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA5208	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.907