Protein profile

PA5276

lipopeptide LppL

Genome: NC_002516.2

Gene: PA5276 lppL Structure source: AlphaFold UniProt P17323

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Amino acids 46

Annotations 1

Features 14

PDB binders 0

Overview

Basic information about this protein and its source genome.

Accession: PA5276
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA5276 lppL
Status: annotated
Amino acids: 46
Structure source: AlphaFold

GO:0009279 A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Unknown

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0009279 A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records

Show feature table

Start	End	DB	Term	Name
4	14	Phobius	SIGNAL_PEPTIDE_H_REGION	Hydrophobic region of a signal peptide.
20	46	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
5	27	TMHMM	TMhelix	Region of a membrane-bound protein predicted to be embedded in the membrane.
1	21	ProSiteProfiles	PS51257	Prokaryotic membrane lipoprotein lipid attachment site profile.
1	20	SignalP_EUK	SignalP-noTM	SignalP-noTM
1	19	Phobius	SIGNAL_PEPTIDE	Signal peptide region
1	21	SignalP_GRAM_POSITIVE	SignalP-TM	SignalP-TM
1	46	PIRSF	PIRSF037657	Lipopeptide_LppL
1	46	InterPro	IPR017254	Lipoprotein, LppL
15	19	Phobius	SIGNAL_PEPTIDE_C_REGION	C-terminal region of a signal peptide.
1	3	Phobius	SIGNAL_PEPTIDE_N_REGION	N-terminal region of a signal peptide.
1	21	SignalP_GRAM_NEGATIVE	SignalP-noTM	SignalP-noTM
9	30	Pfam	PF13627	Prokaryotic lipoprotein-attachment site
9	30	InterPro	IPR032831	Prokaryotic lipoprotein-attachment site

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

No pockets are loaded yet for the displayed AlphaFold model PA5276 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

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Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA5276	AlphaFold	—	—	full sequence	—	Viewing