Protein profile

PA5319

DNA repair protein RadC

Genome: NC_002516.2

Gene: radC Structure source: ColabFold
Export view
Amino acids 224
Annotations 0
Features 19
PDB binders 0
Druggability 0.944

Overview

Basic information about this protein and its source genome.

Accession
PA5319
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
radC
Status
annotated
Amino acids
224
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.944
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

19 records
Show feature table
Start End DB Term Name
101 224 Gene3D G3DSA:3.40.140.10 Cytidine Deaminase, domain 2
11 224 NCBIfam TIGR00608 DNA repair protein RadC
11 224 InterPro IPR001405 Uncharacterised protein family UPF0758
104 222 Pfam PF04002 RadC-like JAB domain
104 222 InterPro IPR025657 RadC-like JAB domain
107 219 CDD cd08071 MPN_DUF2466
107 219 InterPro IPR025657 RadC-like JAB domain
3 80 Pfam PF20582 UPF0758 N-terminal
3 80 InterPro IPR046778 UPF0758, N-terminal
173 178 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature.
173 178 InterPro IPR020891 Uncharacterised protein family UPF0758, conserved site
1 224 PANTHER PTHR30471 DNA REPAIR PROTEIN RADC
1 224 InterPro IPR001405 Uncharacterised protein family UPF0758
122 197 SUPERFAMILY SSF102712 JAB1/MPN domain
102 224 ProSiteProfiles PS50249 MPN domain profile.
102 224 InterPro IPR037518 MPN domain
101 224 FunFam G3DSA:3.40.140.10:FF:000032 DNA repair protein RadC
18 90 SUPERFAMILY SSF47781 RuvA domain 2-like
18 90 InterPro IPR010994 RuvA domain 2-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold PA5319
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
7 0.944
1 0.521