Protein profile

PA5326

hypothetical protein

Genome: NC_002516.2

Gene: PA5326 Structure source: AlphaFold UniProt Q9HTM9
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Amino acids 402
Annotations 4
Features 8
PDB binders 0
Druggability 0.808

Overview

Basic information about this protein and its source genome.

Accession
PA5326
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5326
Status
annotated
Amino acids
402
Structure source
AlphaFold
GO
GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0008721 Catalysis of the reaction: D-serine = pyruvate + NH4+. GO:0036088 The chemical reactions and pathways resulting in the breakdown of D-serine. GO:0051872 The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.808
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

4 GO

Gene Ontology (GO)

4
  • GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
  • GO:0008721 Catalysis of the reaction: D-serine = pyruvate + NH4+.
  • GO:0036088 The chemical reactions and pathways resulting in the breakdown of D-serine.
  • GO:0051872 The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
33 271 Pfam PF01168 Alanine racemase, N-terminal domain
33 271 InterPro IPR001608 Alanine racemase, N-terminal
20 402 CDD cd06814 PLPDE_III_DSD_D-TA_like_3
21 400 PANTHER PTHR28004 ZGC:162816-RELATED
35 267 Gene3D G3DSA:3.20.20.10 Alanine racemase
35 267 InterPro IPR029066 PLP-binding barrel
34 271 SUPERFAMILY SSF51419 PLP-binding barrel
34 271 InterPro IPR029066 PLP-binding barrel

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA5326
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.808
1 0.42
5 0.283