Protein profile

PA5401

hypothetical protein

Genome: NC_002516.2

Gene: PA5401 Structure source: AlphaFold UniProt Q9HTG3
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Amino acids 257
Annotations 1
Features 9
PDB binders 0
Druggability 0.822

Overview

Basic information about this protein and its source genome.

Accession
PA5401
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5401
Status
annotated
Amino acids
257
Structure source
AlphaFold
GO
GO:0009055 A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.822
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0009055 A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
12 190 SMART SM00893 ETF_2
12 190 InterPro IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal
24 217 SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like
9 256 Gene3D G3DSA:3.40.50.620 HUPs
9 256 InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
27 185 Pfam PF01012 Electron transfer flavoprotein domain
27 185 InterPro IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal
26 256 PANTHER PTHR21294 ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT
26 256 InterPro IPR012255 Electron transfer flavoprotein, beta subunit

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA5401
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.822
2 0.767