Protein profile

PA5417

sarcosine oxidase subunit delta

Genome: NC_002516.2

Gene: soxD PA5417 Structure source: AlphaFold UniProt Q9HTE7
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Amino acids 106
Annotations 3
Features 7
PDB binders 0
Druggability 0.84

Overview

Basic information about this protein and its source genome.

Accession
PA5417
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
soxD PA5417
Status
annotated
Amino acids
106
Structure source
AlphaFold
GO
GO:0008115 Catalysis of the reaction: H2O + O2 + sarcosine = formaldehyde + glycine + H2O2. GO:1901053 OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sarcosine. GO:0046653 The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.84
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0008115 Catalysis of the reaction: H2O + O2 + sarcosine = formaldehyde + glycine + H2O2.
  • GO:1901053 OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sarcosine.
  • GO:0046653 The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
1 98 FunFam G3DSA:3.30.2270.10:FF:000002 Sarcosine oxidase subunit delta
4 84 Pfam PF04267 Sarcosine oxidase, delta subunit family
4 84 InterPro IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric
1 98 Gene3D G3DSA:3.30.2270.10 -
1 98 InterPro IPR038561 Sarcosine oxidase subunit delta superfamily
3 87 NCBIfam TIGR01374 sarcosine oxidase subunit delta family protein
3 87 InterPro IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA5417
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.84