Protein profile

PA5491

cytochrome

Genome: NC_002516.2

Gene: PA5491 Structure source: AlphaFold UniProt Q9HT82
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Amino acids 97
Annotations 3
Features 25
PDB binders 0
Druggability 0.794

Overview

Basic information about this protein and its source genome.

Accession
PA5491
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5491
Status
annotated
Amino acids
97
Structure source
AlphaFold
GO
GO:0009055 A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways. GO:0020037 Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. GO:0005506 Binding to an iron (Fe) ion.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.794
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0009055 A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways.
  • GO:0020037 Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
  • GO:0005506 Binding to an iron (Fe) ion.

Sequence Features

Domain/signature hits from InterPro and related databases.

25 records
Show feature table
Start End DB Term Name
19 94 InterPro IPR009056 Cytochrome c-like domain
18 97 Gene3D G3DSA:1.10.760.10 -
18 97 InterPro IPR036909 Cytochrome c-like domain superfamily
1 19 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
18 97 ProSiteProfiles PS51007 Cytochrome c family profile.
18 97 InterPro IPR009056 Cytochrome c-like domain
84 95 PRINTS PR00607 Class IE cytochrome C signature
84 95 InterPro IPR002323 Cytochrome c, class IE
41 51 PRINTS PR00607 Class IE cytochrome C signature
41 51 InterPro IPR002323 Cytochrome c, class IE
30 41 PRINTS PR00607 Class IE cytochrome C signature
30 41 InterPro IPR002323 Cytochrome c, class IE
69 81 PRINTS PR00607 Class IE cytochrome C signature
69 81 InterPro IPR002323 Cytochrome c, class IE
19 94 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III
1 19 Phobius SIGNAL_PEPTIDE Signal peptide region
20 95 SUPERFAMILY SSF46626 Cytochrome c
20 95 InterPro IPR036909 Cytochrome c-like domain superfamily
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 19 SignalP_EUK SignalP-noTM SignalP-noTM
20 97 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
16 19 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
11 96 PANTHER PTHR40942 -
11 96 InterPro IPR002323 Cytochrome c, class IE
4 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA5491
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.794