Protein profile

PA5528

hypothetical protein

Genome: NC_002516.2

Gene: PA5528 Structure source: AlphaFold UniProt Q9HT45
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Amino acids 284
Annotations 0
Features 20
PDB binders 0
Druggability 0.778

Overview

Basic information about this protein and its source genome.

Accession
PA5528
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5528
Status
annotated
Amino acids
284
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.778
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

20 records
Show feature table
Start End DB Term Name
1 23 SignalP_EUK SignalP-noTM SignalP-noTM
30 58 MobiDBLite mobidb-lite consensus disorder prediction
96 116 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
1 23 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
154 282 SUPERFAMILY SSF54427 NTF2-like
154 282 InterPro IPR032710 NTF2-like domain superfamily
1 23 Phobius SIGNAL_PEPTIDE Signal peptide region
33 51 MobiDBLite mobidb-lite consensus disorder prediction
95 117 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
152 283 SMART SM00978 Tim44_a_2
152 283 InterPro IPR007379 Tim44-like domain
16 23 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
117 284 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
24 95 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 284 PANTHER PTHR41542 BLL5807 PROTEIN
158 282 Pfam PF04280 Tim44-like domain
158 282 InterPro IPR007379 Tim44-like domain
68 90 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
4 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA5528
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.44
5 0.399
3 0.201