Protein profile

PA5551

hypothetical protein

Genome: NC_002516.2

Gene: PA5551 Structure source: AlphaFold UniProt Q9HT23
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Amino acids 169
Annotations 1
Features 14
PDB binders 0
Druggability 0.967

Overview

Basic information about this protein and its source genome.

Accession
PA5551
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA5551
Status
annotated
Amino acids
169
Structure source
AlphaFold
GO
GO:0004222 Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.967
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0004222 Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
50 137 Pfam PF01551 Peptidase family M23
50 137 InterPro IPR016047 Peptidase M23
23 138 SUPERFAMILY SSF51261 Duplicated hybrid motif
23 138 InterPro IPR011055 Duplicated hybrid motif
1 23 Phobius SIGNAL_PEPTIDE Signal peptide region
22 148 Gene3D G3DSA:2.70.70.10 Glucose Permease (Domain IIA)
22 148 InterPro IPR011055 Duplicated hybrid motif
51 137 CDD cd12797 M23_peptidase
20 23 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 20 SignalP_EUK SignalP-noTM SignalP-noTM
8 19 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
24 169 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
44 147 PANTHER PTHR21666 PEPTIDASE-RELATED

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA5551
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.967
1 0.312