Protein profile

VK055_0194

sel1 repeat family protein

Genome: KpATCC43816

Gene: AIK78822.1 Structure source: ColabFold
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Amino acids 354
Annotations 1
Features 18
PDB binders 0
Druggability 0.598

Overview

Basic information about this protein and its source genome.

Accession
VK055_0194
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK78822.1
Status
annotated
Amino acids
354
Structure source
ColabFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Periplasmic
ColabFold pLDDT
91.01

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.598
Structure CB_VK055_0194
Pocket Pocket 20
P2Rank 0.069
Structure CB_VK055_0194
Pocket Pocket 1
ColabFold model
FPocket 0.598 · Pocket 20
P2Rank 0.069 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 1 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

18 records
Show feature table
Start End DB Term Name
199 230 SMART SM00671 sel1
199 230 InterPro IPR006597 Sel1-like repeat
129 165 SMART SM00671 sel1
129 165 InterPro IPR006597 Sel1-like repeat
1 20 Phobius SIGNAL_PEPTIDE Signal peptide region
4 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
82 240 SUPERFAMILY SSF81901 HCP-like
16 20 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
21 354 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
54 222 PANTHER PTHR11102 SEL-1-LIKE PROTEIN
332 354 MobiDBLite mobidb-lite consensus disorder prediction
1 18 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
1 20 SignalP_EUK SignalP-noTM SignalP-noTM
33 275 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
33 275 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
233 340 Pfam PF19933 Domain of unknown function (DUF6396)
233 340 InterPro IPR045653 Domain of unknown function DUF6396

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold VK055_0194
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.105
29 0.019
5 0.001
14 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.78 0.069
2 1.8 0.028
3 1.71 0.025
4 1.53 0.019
5 1.12 0.007