Metabolic network

VK055_0340

2,3-dihydroxyphenylpropionate/2, 3-dihydroxicinnamic acid 1,2-dioxygenase

Network centrality 0.01543 top 91.9%
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction in Phenylalanine metabolism, no isoenzyme backup detected, more central than 91.9% of genes in this genome, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

1.13.11.16-RXN

EC 1.13.11.16 · 1.13.11.16-RXN · not reversible · no isoenzyme backup

Consuming chokepoint
3-(2,3-dihydroxyphenyl)propanoate dioxygen
H+ (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate

RXN-12073

EC 1.13.11.16 · RXN-12073 · not reversible · no isoenzyme backup

Producing & consuming chokepoint
2,3-dihydroxy-trans-cinnamate dioxygen
(2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate H+

Imported from KpATCC43816.sbml · 2026-07-09