KEGG:map00360

Phenylalanine metabolism

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 24
Proteins 18
Metabolites 43
Chokepoints 8

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

MODEL Unassigned metabolic reactions 38 shared KEGG Citrate cycle (TCA cycle) 3 shared KEGG Glycolysis / Gluconeogenesis 2 shared KEGG Glycine, serine and threonine metabolism 2 shared KEGG Valine, leucine and isoleucine degradation 2 shared KEGG Benzoate degradation 2 shared KEGG Aminoacyl-tRNA biosynthesis 1 shared KEGG Pyrimidine metabolism 1 shared KEGG Alanine, aspartate and glutamate metabolism 1 shared KEGG Pentose phosphate pathway 1 shared KEGG Glycerophospholipid metabolism 1 shared KEGG Phosphonate and phosphinate metabolism 1 shared KEGG Cysteine and methionine metabolism 1 shared KEGG Arginine and proline metabolism 1 shared KEGG Lysine biosynthesis 1 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

1.13.11.16-RXN

EC 1.13.11.16 · R04376 · 1.13.11.16-RXN · not reversible

consuming
3-(2,3-dihydroxyphenyl)propanoate dioxygen
→
(2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate H+
VK055_0340

MHPELY-RXN

EC 4.1.3.39 · R00750 · MHPELY-RXN · not reversible

(S)-4-hydroxy-2-oxopentanoate
→
acetaldehyde pyruvate
VK055_0344

MHPHYDROXY-RXN

EC 1.14.13.127 · R06786 · MHPHYDROXY-RXN · not reversible

producing
3-(3-hydroxyphenyl)propanoate H+ NADH dioxygen
→
3-(2,3-dihydroxyphenyl)propanoate H2O NAD+
VK055_0339

RXN0-2042

EC 1.14.13.149 · R09838 · RXN0-2042 · not reversible

both
phenylacetyl-CoA H+ NADPH dioxygen
→
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA H2O NADP+
VK055_1038

RXN0-2044

EC 1.1.1.35 · R06941 · RXN0-2044 · reversible

(3S)-hydroxyadipyl-CoA NAD+
⇌
3-oxoadipoyl-CoA H+ NADH
No mapped protein

RXN0-6510

EC 5.3.3.18 · R09837 · RXN0-6510 · not reversible

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
→
2-oxepin-2(3H)-ylideneacetyl-CoA
No mapped protein

RXN0-6512

EC 2.3.1.223 · R09839 · RXN0-6512 · not reversible

3-oxo-5,6-didehydrosuberyl-CoA coenzyme A
→
(2E)-5-carboxy-2-pentenoyl-CoA acetyl-CoA
No mapped protein

RXN-10040

EC 1.14.13.127 · R06787 · RXN-10040 · not reversible

3-coumarate H+ NADH dioxygen
→
2,3-dihydroxy-trans-cinnamate H2O NAD+
No mapped protein

RXN-10819

EC 6.2.1.30 · R02539 · RXN-10819 · not reversible

both
phenylacetate ATP coenzyme A
→
phenylacetyl-CoA AMP diphosphate
VK055_1031

RXN-12070

EC 3.7.1.14 · R06789 · RXN-12070 · not reversible

consuming
(2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate H2O
→
(2Z)-2-hydroxypenta-2,4-dienoate fumarate H+
VK055_0341

RXN-12071

EC 1.3.1.87 · R06785 · RXN-12071 · not reversible

(2E)-3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate NAD+
→
2,3-dihydroxy-trans-cinnamate H+ NADH
No mapped protein

RXN-12072

EC 1.14.12.19 · R06783 · RXN-12072 · not reversible

trans-cinnamate H+ NADH dioxygen
→
(2E)-3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate NAD+
No mapped protein

RXN-12073

EC 1.13.11.16 · R06788 · RXN-12073 · not reversible

both
2,3-dihydroxy-trans-cinnamate dioxygen
→
(2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate H+
VK055_0340

RXN-7700

EC 1.1.1.1 · R02611 · RXN-7700 · reversible

2-phenylethanol NAD+
⇌
phenylacetaldehyde H+ NADH
VK055_0526

RXNMETA-12671

EC 3.3.2.12 · R09836 · RXNMETA-12671 · not reversible

2-oxepin-2(3H)-ylideneacetyl-CoA H2O
→
3-oxo-5,6-didehydrosuberyl-CoA semialdehyde
No mapped protein

RXNMETA-12672

EC 1.2.1.91 · R09820 · RXNMETA-12672 · not reversible

3-oxo-5,6-didehydrosuberyl-CoA semialdehyde H2O NADP+
→
3-oxo-5,6-didehydrosuberyl-CoA H+ NADPH
No mapped protein