Protein profile

VK055_0353

NMT1-like family protein

Genome: KpATCC43816

Gene: AIK78979.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GR32
Export view
Amino acids 345
Annotations 0
Features 13
PDB binders 0
Druggability 0.341

Overview

Basic information about this protein and its source genome.

Accession
VK055_0353
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK78979.1
Status
annotated
Amino acids
345
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
87.75

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.341
Structure A0A0H3GR32
Pocket Pocket 18
P2Rank 0.8
Structure A0A0H3GR32
Pocket Pocket 1
ColabFold model
FPocket 0.503 · Pocket 1
P2Rank 0.808 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 13 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
30 345 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
11 21 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
47 273 Pfam PF13379 NMT1-like family
49 276 SUPERFAMILY SSF53850 Periplasmic binding protein-like II
1 10 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 29 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
59 288 Gene3D G3DSA:3.40.190.10 -
1 29 Phobius SIGNAL_PEPTIDE Signal peptide region
1 29 ProSiteProfiles PS51318 Twin arginine translocation (Tat) signal profile.
1 29 InterPro IPR006311 Twin-arginine translocation pathway, signal sequence
14 293 PANTHER PTHR30024 ALIPHATIC SULFONATES-BINDING PROTEIN-RELATED
133 235 Gene3D G3DSA:3.40.190.10 -
22 29 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GR32
AlphaFold — — full sequence — Viewing
ColabFold VK055_0353
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
18 0.341
3 0.006
16 0.004

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 20.88 0.8
2 7.9 0.354
3 3.19 0.087
4 1.6 0.021
5 1.33 0.013