Protein profile

VK055_0383

CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI

Genome: KpATCC43816

Gene: cas7 AIK79009.1 Structure source: Experimental + ColabFold UniProt A0A378B8S3
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Amino acids 324
Annotations 0
Features 4
PDB binders 0
Druggability 0.855

Overview

Basic information about this protein and its source genome.

Accession
VK055_0383
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
cas7 AIK79009.1
Status
annotated
Amino acids
324
Structure source
Experimental + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
92.41

Selected Druggability evidence

PDB experimental structure

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.855
Structure 8JI9
Pocket Pocket 16
P2Rank 0.583
Structure 8JI9
Pocket Pocket 1
ColabFold model
FPocket 0.559 · Pocket 3
P2Rank 0.048 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 18 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
8 309 NCBIfam TIGR01869 type I-E CRISPR-associated protein Cas7/Cse4/CasC
8 309 InterPro IPR010148 CRISPR-associated protein, CT1975
10 308 Pfam PF09344 CT1975-like protein
10 308 InterPro IPR010148 CRISPR-associated protein, CT1975

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 8JI9
X-ray 2.54 Å A,C
98.1% 7-324
PDBe RCSB PDBj File
Viewing
ColabFold VK055_0383
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
42 0.855

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 10.96 0.588
2 6.57 0.333
3 6.08 0.301
4 3.64 0.137
5 3.35 0.119