Protein profile

VK055_0418

hypothetical protein

Genome: KpATCC43816

Gene: AIK79044.1 Structure source: AlphaFold + ColabFold UniProt A0A060VHA1
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Amino acids 302
Annotations 1
Features 4
PDB binders 0
Druggability 0.102

Overview

Basic information about this protein and its source genome.

Accession
VK055_0418
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79044.1
Status
annotated
Amino acids
302
Structure source
AlphaFold + ColabFold
GO
GO:0006974 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
27.513
Localization
Cytoplasmic
ColabFold pLDDT
92.21

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.102
Structure A0A060VHA1
Pocket Pocket 2
P2Rank 0.227
Structure A0A060VHA1
Pocket Pocket 1
ColabFold model
FPocket 0.272 · Pocket 21
P2Rank 0.123 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 7 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0006974 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
70 292 PANTHER PTHR38785 HOMOLOG OF VIRK
70 292 InterPro IPR007488 Protein of unknown function DUF535
60 288 Pfam PF04393 Protein of unknown function (DUF535)
60 288 InterPro IPR007488 Protein of unknown function DUF535

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A060VHA1
AlphaFold — — full sequence — Viewing
ColabFold VK055_0418
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 4.57 0.196
2 3.03 0.1
3 1.42 0.018