Protein profile

VK055_0583

acetyltransferase family protein

Genome: KpATCC43816

Gene: AIK79206.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GQF6
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Amino acids 169
Annotations 1
Features 9
PDB binders 0
Druggability 0.113

Overview

Basic information about this protein and its source genome.

Accession
VK055_0583
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79206.1
Status
annotated
Amino acids
169
Structure source
AlphaFold + ColabFold
GO
GO:0016747 Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
29.008
Localization
Cytoplasmic
ColabFold pLDDT
93.03

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.113
Structure A0A0H3GQF6
Pocket Pocket 11
P2Rank 0.885
Structure A0A0H3GQF6
Pocket Pocket 1
ColabFold model
FPocket 0.527 · Pocket 1
P2Rank 0.906 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 53 / 4744 genomes with a hit
Normalized 0.011

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016747 Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
47 143 PANTHER PTHR43877 -
5 137 SUPERFAMILY SSF55729 Acyl-CoA N-acyltransferases (Nat)
5 137 InterPro IPR016181 Acyl-CoA N-acyltransferase
3 162 Gene3D G3DSA:3.40.630.30 -
13 157 ProSiteProfiles PS51186 Gcn5-related N-acetyltransferase (GNAT) domain profile.
13 157 InterPro IPR000182 GNAT domain
53 115 CDD cd04301 NAT_SF
33 132 Pfam PF00583 Acetyltransferase (GNAT) family
33 132 InterPro IPR000182 GNAT domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GQF6
AlphaFold — — full sequence — Viewing
ColabFold VK055_0583
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 11.84 0.628
2 4.87 0.218
3 1.55 0.023
4 1.4 0.017
5 1.12 0.008