Protein profile

VK055_0651

putative periplasmic protein

Genome: KpATCC43816

Gene: AIK79274.1 Structure source: AlphaFold + ColabFold UniProt A6T9J3
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Amino acids 134
Annotations 0
Features 18
PDB binders 0
Druggability 0.029

Overview

Basic information about this protein and its source genome.

Accession
VK055_0651
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79274.1
Status
annotated
Amino acids
134
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
56.923
DEG E-value
1.56e-52
Localization
Unknown
ColabFold pLDDT
76.24

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.029
Structure A6T9J3
Pocket Pocket 3
P2Rank
Structure A6T9J3
Pocket No pockets
ColabFold model
FPocket 0.61 · Pocket 6
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 49 / 4744 genomes with a hit
Normalized 0.01

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

18 records
Show feature table
Start End DB Term Name
1 19 SignalP_EUK SignalP-noTM SignalP-noTM
15 19 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
21 130 Gene3D G3DSA:2.40.50.200 -
21 130 InterPro IPR036700 Bacterial OB-fold superfamily
1 19 Phobius SIGNAL_PEPTIDE Signal peptide region
5 128 NCBIfam NF033674 NirD/YgiW/YdeI family stress tolerance protein
1 128 PANTHER PTHR36571 PROTEIN YGIW
4 14 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
30 128 SUPERFAMILY SSF101756 Hypothetical protein YgiW
30 128 InterPro IPR036700 Bacterial OB-fold superfamily
24 44 MobiDBLite mobidb-lite consensus disorder prediction
30 128 Pfam PF04076 Bacterial OB fold (BOF) protein
30 128 InterPro IPR005220 Bacterial OB-fold
1 130 NCBIfam TIGR00156 YgiW/YdeI family stress tolerance OB fold protein
1 130 InterPro IPR016052 YgiW/YdeI
1 19 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
20 134 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A6T9J3
AlphaFold — — full sequence — Viewing
ColabFold VK055_0651
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer