Protein profile

VK055_0741

hypothetical protein

Genome: KpATCC43816

Gene: AIK79364.1 Structure source: AlphaFold + ColabFold UniProt A0AAX0P7E1
Export view
Amino acids 159
Annotations 0
Features 9
PDB binders 0
Druggability 0.69

Overview

Basic information about this protein and its source genome.

Accession
VK055_0741
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79364.1
Status
annotated
Amino acids
159
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
30.0
Localization
Extracellular
ColabFold pLDDT
92.44

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.69
Structure A0AAX0P7E1
Pocket Pocket 5
P2Rank 0.023
Structure A0AAX0P7E1
Pocket Pocket 1
ColabFold model
FPocket 0.573 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 29 / 4744 genomes with a hit
Normalized 0.006

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
1 149 PANTHER PTHR34319 MAJOR EXPORTED PROTEIN
1 159 Gene3D G3DSA:2.30.110.20 -
1 159 InterPro IPR036624 Hcp1-like superfamily
3 155 SUPERFAMILY SSF141452 Hcp1-like
3 155 InterPro IPR036624 Hcp1-like superfamily
1 155 NCBIfam TIGR03344 type VI secretion system tube protein TssD/Hcp
1 155 InterPro IPR008514 Type VI secretion system effector Hcp
8 142 Pfam PF05638 Type VI secretion system effector, Hcp
8 142 InterPro IPR008514 Type VI secretion system effector Hcp

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0AAX0P7E1
AlphaFold — — full sequence — Viewing
ColabFold VK055_0741
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.471
1 0.034
2 0.027
4 0.001

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.65 0.023