Protein profile

VK055_1005

plasma membrane proteolipid Pmp3

Genome: KpATCC43816

Gene: AIK79628.1 pmp3 Structure source: AlphaFold + ColabFold UniProt A0A0H3GMN1
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Amino acids 52
Annotations 1
Features 11
PDB binders 0

Overview

Basic information about this protein and its source genome.

Accession
VK055_1005
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79628.1 pmp3
Status
annotated
Amino acids
52
Structure source
AlphaFold + ColabFold
GO
GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
CytoplasmicMembrane
ColabFold pLDDT
95.79

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket
Structure A0A0H3GMN1
Pocket No pockets
P2Rank
Structure A0A0H3GMN1
Pocket No pockets
ColabFold model
FPocket 0.695 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 83 / 4744 genomes with a hit
Normalized 0.017

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
49 52 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
4 51 PANTHER PTHR21659 HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED
4 51 InterPro IPR000612 Proteolipid membrane potential modulator
7 22 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature.
7 22 InterPro IPR000612 Proteolipid membrane potential modulator
23 48 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
2 20 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
25 47 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 22 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
3 48 Pfam PF01679 Proteolipid membrane potential modulator
3 48 InterPro IPR000612 Proteolipid membrane potential modulator

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GMN1
AlphaFold — — full sequence — Viewing
ColabFold VK055_1005
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer