Protein profile

VK055_1009

hypothetical protein

Genome: KpATCC43816

Gene: AIK79632.1 Structure source: AlphaFold + ColabFold UniProt A0A483L2X1
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Amino acids 266
Annotations 1
Features 8
PDB binders 0
Druggability 0.639

Overview

Basic information about this protein and its source genome.

Accession
VK055_1009
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79632.1
Status
annotated
Amino acids
266
Structure source
AlphaFold + ColabFold
GO
GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
95.3

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.639
Structure A0A483L2X1
Pocket Pocket 6
P2Rank 0.738
Structure A0A483L2X1
Pocket Pocket 1
ColabFold model
FPocket 0.69 · Pocket 4
P2Rank 0.704 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 62 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
26 181 Gene3D G3DSA:3.40.50.620 HUPs
26 181 InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
64 171 CDD cd06259 YdcF-like
64 171 InterPro IPR003848 Domain of unknown function DUF218
7 253 PANTHER PTHR30336 INNER MEMBRANE PROTEIN, PROBABLE PERMEASE
8 250 Gene3D G3DSA:1.10.3620.10 YdcF like domain
39 172 Pfam PF02698 DUF218 domain
39 172 InterPro IPR003848 Domain of unknown function DUF218

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A483L2X1
AlphaFold — — full sequence — Viewing
ColabFold VK055_1009
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.294
12 0.107
8 0.005
9 0.002

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 17.85 0.738
2 2.33 0.049
3 1.28 0.011